Drug Class and Mechanism
Sibutramine is used for weight loss by changing composition of neurotransmitters in the brain. The process by which neurotransmitters attach themselves to other nerves and are taken up by the same nerves is called reuptake. Sibutramine stops this process of neurotransmitters like dopamine and serotonin. This causes the balance of neurotransmitters to alter thereby affecting the functioning of nerves. Patients taking this drug have shown 5-10% reduction in their base weight. It also helps to improve blood lipids.