1.
Drug Class and Mechanism
Megestrol
is mainly used to fight cancer. It also happens to be a synthetic female
hormone that belongs to the progesterone group. Progesterone is a hormone that
is mainly produced by the female. It helps to control the menstrual flow in
women apart from other functions of the body.
2.
Prescription, Storage and Description
Megestrol
is available as a prescription drug under the brand names, Megace and Megace
ES. No generic of this drug is available. It is mainly prescribed for breast
cancer and cancer of the uterus that is known as carcinoma. It does not treat
cancer by itself but is in addition to therapy. It is also prescribed for
weight maintenance in patients suffering from AIDS. It is an appetite stimulant
and is commonly used in women. Megestrol should be stored in a dry room and at
room temperature. The oral suspension should ideally be stored in a
refrigerator and in a very tightly sealed container. The dose of this medicine
is administered for several months. Doses of 800 mg everyday are used for weight
loss. It can be taken with food or without food. However, when taken with food
better absorption is possible. Oral suspension should be shaken and not stirred
before consuming.
3. Megestrol Drug Interactions
Megestrol
greatly increases appetite and therefore weight gain is commonly seen. This is
not due to water retention but an outcome of too much food intake.
4.
How to Use Megestrol
It
is necessary to follow the doctor’s prescription and take the medicine orally.
Maximum benefit can be achieved by taking the medication regularly and for a
prolonged time span.
5.
Megestrol Side Effects
The
most common side effects are rashes on skin, nausea, impotency and gas in
stomach also known as flatulence. It also causes weight gain, changes in
sleeping and appetite patterns. A decreased sex drive is also seen in some
cases. In case of women; irregular changes in menses is common, accompanied by
unpredictable bleeding. Rare side effects are a rapid heart beat, swelling of
limbs, headache, chest pain, mood swings, confusion, numbness of a part of the
body, rapid changes in vision, disturbed speech and breathing issues.
Hypertension is also possible in some cases. Increased dose also increases the
side effects. Very serious allergic reactions are not common. However at times;
rashes, itching of skin and swelling of throat, face and tongue are observed.
Taking this drug during pregnancy is not recommended as it can cause defects in
the fetus. It interferes with the functioning of hormones and should not be
taken if breast-feeding. It is not advisable for women to consume this drug who
are potentially capable of becoming pregnant. Birth control methods are
compulsory for women who are on megestrol but are still fertile.
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